December 11, 2012

How Cancer Risk and Obesity are Linked

What are the numbers?

  • A body mass index (BMI) between 25 and 30 kg/m2 defines overweight
  • A BMI greater than 30 kg/m2 defines obesity
  • The number of overweight and obese individuals in the U.S. has consistently increased over the past 50 years
  • The latest data shows 75% of adults and 33% of children are considered overweight or obese
  • SEER Epidemiology data suggest that each 5-point increase in BMI results in an increased risk of developing cancer that ranges from 13% to 60% depending on cancer type

 What cancer type and what may be the mechanism?

  • Esophageal, colorectal, pancreatic, kidney cell, postmenopausal breast and endometrial cancers
  • weight-associated changes in the synthesis and action of sex hormones, insulin, insulin-like growth factor and other cellular growth factors
  • systematic inflammation, oxidative stress and altered immune response
Moderation in both diet and exercise can be cancer preventing. More information can be found at

Robert G. Tupac, DDS, FACP, Inc., 
Diplomate, American Board of Prosthodontics
(661) 325-1275 |
5060 California Ave., #170, Bakersfield, CA 93309

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