The United States Preventive Services Task Force (USPSTF) has published draft recommendations for preventive therapy in women with high risk of breast cancer. Risk assessment is based on the National Cancer Institute (NCI) Breast Cancer Risk Assessment Tool, which predicts 5-year cancer risk based on an individual's age, family history, ethnicity, age at first menstruation, age at first live childbirth, and personal history of ductal carcinoma, lobular carcinoma, or breast biopsies.
The recommendations are for women between the ages of 40 and 70, who have no prior diagnosis of invasive breast cancer, ductal cancer, lobular cancer, and no history of blood clots or stroke. Preventive therapy using tamoxifen or raloxifene in this group was shown to reduce the risk of invasive breast cancer by 30-56%.
For greater detail, go to: www.chemotherapyadvisor.com
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